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Network connectivity is only as good as the routing information used by hosts to locate servers, clients, and service endpoints on the network IP-routing algorithms attempt to handle redundancy and dynamic recovery from failures; however, they also introduce new complexities that result in sometimesbaffling failures Asymmetric routes, incomplete or incorrect routing information, or networks with many hops between redundant connections also contribute to network failures Asymmetric routes occur when a client finds the server without problem but the server cannot send a reply back to the client because it lacks routing information This is possible if the server is behind a firewall that blocks some routing information, if the server uses static routing information, or if a router along the path is sending incorrect route updates.

Figure 8.3. Probability of nding at least one antibody than recognizes any given epitope as a function of repertoire size and threshold Kd value.5 [Reprinted, with permission, from A. D. Grif ths and D. S. Taw k, Current Opinion in Biotechnology 2, 2000, 338 353. Man-Made Enzymes From Design to In Vitro Compartmentalization . # 2000 Elsevier Science Ltd.]

Note that it s the server s return path that creates the network failure; if the client can t find the server, the client-side application will complain about an unreachable host or network A client sending a request on its happy way turns unhappy when the reply is discarded at the server, silently, due to an asymmetric routing configuration NFS system administrators puzzled by nfs_server: bad sendreply error messages can thank asymmetric routes for their problems This error is caused by an NFS server s inability to return a client request Again, using the ping utility, or more prudent examination with a tool such as traceroute, the system administrator can locate the trouble spots and provide ongoing monitoring of the round-trip health of your network Technically, any host with two or more network interfaces can function as a router.

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This doesn t always mean that it should, however, as routing is CPUintensive and will degrade performance for other applications Usually, hosts that accidentally route packets do a poor job of it Look for unwanted IP routing using netstat -s (in Windows or Solaris) Finally, once a router fails, the network needs to construct a redundant path to the networks on the far side of the failure If there are multiple routers connecting two networks, the secondary routers will appear in hosts routing tables during subsequent routing table updates For example, using the Routing Information Protocol (RIP), updates are sent by active routing hosts every.